Saccharomyces boulardii is a yeast that happens to function like a probiotic in the body.

It was first isolated from lychee and mangosteen in 1923 by French scientist Henri Boulard after observing the locals of Southeast Asia chewing on the skin of these fruits in an attempt to control the symptoms of cholera.

Long used in certain systems of medicine and extensively studied for various indication, Saccharomyces boulardii is now available in dietary supplement form.

Saccharomyces boulardii is bestowed with following characteristics which favour it as strong candidate as a probiotics

  • It survives passage to its target organ (most commonly the colon) and surviving oral doses have been found to be effective.
  • Unique advantage of being one of the few yeasts that it survives and do best at human body temperatures (37°C).
  • In dried freeze form, boulardii survives gastric acid and bile
  • boulardii is naturally resistant to antibiotics, so that it can survives when taken along with antibiotics. S. boulardii levels are higher in patients with disturbed intestinal microbiota (due to antibiotic exposure) compared to patients without antibiotic exposure. This helps it to prevent antibiotic associated diarrhoea by replenishing lost other good bacteria, along with bad ones, due to effect of antibiotics.
  • boulardii is resistant to protein breaking enzymes so that it survives in digestive fluid containing such enzymes and can confer its action effectively
  • boulardii competes with and successfully sustains in presence of bad bugs (pathogenic microorganisms).
  • When taken orally, it attains required level (steady-state concentrations) within 3 days and leaves the place when task is over (cleared within 3–5 days after it is discontinued).

Doctors have recommended it in variety of gastrointestinal disorders. Researchers saw positive results when they used S. boulardii to treat acute diarrhea in both children and adult, C. difficile infection(severe form of diarrhoea affecting large intestine), diarrhea due to parasites (Giardia lamblia). It helps to prevent antibiotic-associated diarrhea, Traveler’s diarrhea and diarrhea associated with tube feeding.

  1. boulardii can also help to treat other ailments, such as lactose intolerance, and might even have a future in the treatment of acne, urinary tract infections, vaginal yeast infections, Human immunodeficiency virus (HIV)-related Diarrhea, high cholesterol, fever blisters, and canker sores. It seems to improve the quality of life of people with irritable bowel syndrome (IBS) as well as inflammatory bowel syndrome (IBD, Crohn’s disease, ulcerative colitis).

About Sanzyme Biologics

Sanzyme Biologics is a probiotic producer based in Hyderabad, India. Sanzyme produces more than 30 distinct strains in a dedicated probiotic manufacturing facility located in Genome Valley, located in the outskirts of Hyderabad.

Sanzyme produces its own S. boulardii strain – SNZ 1986. Details on this strain can be found here:

For further details please contact us on: